What are you trying to do? Articulate your objectives using absolutely no jargon.
I am an engineer and neuroscientist in the field of Radiology with 25 years of experience using imaging to study neurodegenerative disease and CNS disorders and developing creative methods to investigate brain function. My research goal is to make a significant impact on therapeutic and diagnostic options for neurological disorders. I pioneered research at the University of Washington that applied low dose microtubule stabilizers via intranasal administration to treat Alzheimer’s disease and brain injury. At the University of Utah, I partnered with world-experts in therapeutic drug delivery to advance this idea with a novel polymer-drug compound.
How is it done today, and what are the limits of current practice?
Treatments for neurodegenerative diseases and neuronal injuries are few and have limited effectiveness.
What is new in your approach and why do you think it will be successful?
Our therapeutic approach stabilizes microtubules with targeted delivery to the CNS. Microtubule function not only underlies the neuronal cytoskeleton and is critical for essential processes such as axonal transport, but also other structural and functional aspects of brain function such as astrocyte blood-brain-barrier integrity and microglia motility and proliferation.
Who cares? If you are successful, what difference will it make?
If we succeed in slowing or reversing neurodegeneration it will significantly impact CNS health for millions, perhaps billions of people worldwide.