The Office of the Vice President for Research is seeking interdisciplinary and transformative project concepts for the W. M. Keck Foundation. Keck seeks to benefit humanity by supporting projects in two specific areas (1) medical research and (2) science and engineering, that are distinctive and novel in their approach, question the prevailing paradigm, or have the potential to break open new territory in a field. Funding requests are for $1,000,000 in direct costs over three years. Indirect costs are not supported. Larger budget requests and award extensions are not allowed.