Vice President for Research

Below is a list of recently identified external funding opportunities from the National Institute of Health (NIH). These are provided by an external consulting partner. Please ensure you review each program carefully for full program/eligibility details. If anything listed here is considered a Limited Submission Opportunity (LSO) please contact VPRGrants@utah.edu for assistance/information on the internal selection process.

---

NIH Small Research Grant Program
Sponsor	Health and Human Services (HHS)/National Institutes of Health (NIH)
ID Number/Solicitation Link	PA-25-302
Application Due Date	January 7, 2028
Summary	The NIH Small Research Grant Program supports small research projects that can be carried out in a short period of time with limited resources. This program supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. This Notice of Funding Opportunity does not accept applications proposing clinical trial(s).

NIDDK Catalyst Award
Sponsor	Health and Human Services (HHS)/National Institutes of Health (NIH)
ID Number/Solicitation Link	RFA-DK-26-006
Application Due Date	July 18, 2025
Summary	The NIDDK Catalyst Award is designed to complement NIDDK's traditional, investigator-initiated grant programs by supporting individual scientists who propose pioneering and transformational studies in topic areas of interest to NIDDK's Division of Diabetes, Endocrinology and Metabolic Diseases, and to NIDDK's Division of Digestive Diseases and Nutrition. Applications should be focused on major scientific challenges and have the potential to produce an unusually high impact on diseases and conditions that are central to the mission of these two divisions within NIDDK. To be considered responsive to this initiative, the proposed research should reflect new and novel scientific directions that are distinct from concepts and approaches being pursued in the investigators research program or elsewhere.

NIH Exploratory/Developmental Research Project Grant
Sponsor	Health and Human Services (HHS)/National Institutes of Health (NIH)
ID Number/Solicitation Link	PA-25-304
Application Due Date	January 7, 2028
Summary	The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.

NHLBI Clinical Trial Pilot Studies
Sponsor	Health and Human Services (HHS)/National Institutes of Health (NIH)
ID Number/Solicitation Link	PAR-25-032
Application Due Date	January 7, 2027
Summary	This NOFO intends to support studies that are both necessary and sufficient to inform the planning of a Phase II-IV clinical trial within NHLBI's mission. The NHLBI expects that applications to this NOFO will describe the planned clinical trial and in so doing demonstrate that the proposed (R34) research is scientifically necessary to design or plan the subsequent trial. Furthermore, this NOFO will support research projects that are designed to provide results that will be sufficient to inform the future trial without further studies. The planned Phase II, III, or IV trial must be primarily intended to test the efficacy, safety, clinical management, or implementation of intervention(s) in the prevention and/or treatment of heart, lung, blood, and sleep disorders.

NIH Research Project Grant
Sponsor	Health and Human Services (HHS)/National Institutes of Health (NIH)
ID Number/Solicitation Link	PA-25-305
Application Due Date	January 7, 2028
Summary	The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s). This Parent Notice of Funding Opportunity Announcement requires that at lease 1 clinical trial be proposed. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.

NIH Research Project Grant
Sponsor	Health and Human Services (HHS)/National Institutes of Health (NIH)
ID Number/Solicitation Link	PA-25-301
Application Due Date	January 7, 2028
Summary	The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s). The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions. This Notice of Funding Opportunity does not accept applications proposing clinical trial(s).

Ultra-Rare Gene-based Therapy (URGenT) Network Resource Access
Sponsor	Health and Human Services (HHS)/National Institutes of Health (NIH)
ID Number/Solicitation Link	PAR-25-326
Application Due Date	January 3, 2028
Summary	The purpose of this NOFO is to provide investigators with a mechanism to access contract research/medical organizations (CROs/CMOs) and subject matter experts (SMEs) within the NINDS Ultra-Rare Gene-based Therapy (URGenT) Network to support planning, manufacturing, and limited nonclinical therapeutic development efforts.

NIH Research Project Grant
Sponsor	Health and Human Services (HHS)/National Institutes of Health (NIH)
ID Number/Solicitation Link	PA-25-303
Application Due Date	January 7, 2028
Summary	The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s). This Parent Notice of Funding Opportunity is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should submit under this NOFO include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind.

NIH Research Project Grant
Sponsor	Health and Human Services (HHS)/National Institutes of Health (NIH)
ID Number/Solicitation Link	PA-25-305
Application Due Date	January 7, 2028
Summary	The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s). This Parent Notice of Funding Opportunity Announcement requires that at least 1 clinical trial be proposed. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.

NIH Exploratory/Developmental Research Project Grant
Sponsor	Health and Human Services (HHS)/National Institutes of Health (NIH)
ID Number/Solicitation Link	PA-25-307
Application Due Date	January 7, 2028
Summary	The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. This Parent Notice of Funding Opportunity is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research.

Elucidating Immunometabolic Responses to HIV Infection that Increase TB or HBV Risk
Sponsor	Health and Human Services (HHS)/National Institutes of Health (NIH)
ID Number/Solicitation Link	PAR-25-315
Application Due Date	January 7, 2028
Summary	The purpose of this NOFO is to support research to elucidate how HIV-induced immunometabolic alterations, in a host suppressed on combination antiretroviral therapy (cART-suppressed), impact the immune response and increase risk for poor outcomes due to a second, potentially long-term, infection such as Mycobacterium tuberculosis (Mtb) or hepatitis B virus (HBV). This NOFO aims to support research to define how HIV-driven alterations to immunometabolism affect immune cell regulation, cell-cell interactions, response to treatment, and, ultimately, tuberculosis (TB) and HBV disease progression.

Translational Efforts to Advance Gene-based Therapies for Ultra-Rare Neurological And Neuromuscular Disorders
Sponsor	Health and Human Services (HHS)/National Institutes of Health (NIH)
ID Number/Solicitation Link	PAR-25-327
Application Due Date	October 8, 2027
Summary	The Ultra-Rare Gene-Based Therapy (URGenT) network supports Investigational New Drug (IND)-enabling studies and planning activities for First-in-Human (FIH) clinical testing of gene-based or transcript-directed therapeutics, such as oligonucleotides and viral-based gene therapies, for ultra-rare neurological or neuromuscular disorders. The goal of this announcement is to accelerate the development of a promising clinical candidate with robust biological rationale and demonstrated proof of concept (POC) data for the intended approach in a model system relevant to a specified patient population towards an IND filing and the initiation of a clinical trial.

NIAID, NIDDK, NIDA, and NIAAA Research Opportunities for New and “At-Risk” Investigators
Sponsor	Health and Human Services (HHS)/National Institutes of Health (NIH)
ID Number/Solicitation Link	PA-25-249
Application Due Date	September 7, 2025
Summary	SRF Reissue - The purpose of this NOFO is to encourage applications for research projects within the mission of either the NIAID mission or the NIDDK. This NOFO seeks to support either (a) a New Investigator (NI), an individual who has not previously competed successfully for substantial, independent funding from NIH, or (b) are an 'At-Risk' investigator, an individual who had prior support as a PD/PI on a substantial independent research award and unless successful in securing a substantial research grant award in the current fiscal year, will have no substantial research grant funding in the following fiscal year, from diverse backgrounds, including those from groups underrepresented in the health-related sciences. The purpose of this funding opportunity announcement is to encourage applications for research projects within the mission of either the NIAID or the NIDDK.

Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment
Sponsor	Health and Human Services (HHS)/National Institutes of Health (NIH)
ID Number/Solicitation Link	PAR-25-337
Application Due Date	January 7, 2028
Summary	Through this NOFO, the National Cancer Institute (NCI) intends to stimulate efforts to translate scientific discoveries and engineering developments into methods or tools that address problems in basic research to understand disease, or in applied research to assess risk, detect, prevent, diagnose, treat, and/or manage disease. The rationale is to deliver new capabilities to meet evolving requirements for technologies and methods relevant to the advance of research and delivery of care in pre-clinical, clinical and non-clinical settings, domestic or foreign, for conditions and diseases within the missions of participating institutes.

Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment
Sponsor	Health and Human Services (HHS)/National Institutes of Health (NIH)
ID Number/Solicitation Link	PAR-25-338
Application Due Date	January 7, 2028
Summary	Through this NOFO, the National Cancer Institute (NCI) intends to stimulate efforts to translate scientific discoveries and engineering developments into methods or tools that address problems in basic research to understand disease, or in applied research to assess risk, detect, prevent, diagnose, treat, and/or manage disease. The rationale is to deliver new capabilities to meet evolving requirements for technologies and methods relevant to the advance of research and delivery of care in pre-clinical, clinical and non-clinical settings, domestic or foreign, for conditions and diseases within the missions of participating institutes.